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Julien Miracle Baby

Hi there, some of you may know us and others may not. Thank you in advance for reading our story.  My name is Patricia and my husband Ken and I just had a beautiful baby boy named “Julien” on July 14th.  When I was pregnant, many people told me that “it takes a village” to raise a child. I didn’t fully understand what that meant until now. We are reaching out to see if our “village” and “neighboring towns” would be willing to help us with the cost of a life-changing treatment for our baby Julien.


Here is our story:


On Friday July 13th, I went about my day as usual. I went to work, went out for lunch, etc. I noticed that I didn’t feel the baby move so I called my husband to let him know. I remember friends telling me that the baby doesn’t move as much at the very end of a pregnancy (especially if he is on the larger side like Julien was) so I assumed it was ok. I went home from work and drank a green tea latte which wasn’t something I normally drank while I was pregnant but I knew that the caffeine would make the baby move a little. Nothing. Ken got home from work and I told him that I was concerned so we called my midwife. She told me to come to Northside Hospital (which is where I was going to deliver anyway) and that she was on call and would see me there. When we arrived, they hooked me up to an IV and a heartrate and fetal movement monitor. His heartrate was very strong, however the fetal movement line was very flat. They put me on a sugar water IV to see if it would increase fetal movement and it didn’t. The decision was made to slowly induce me so that we could get the baby out without much stress. My midwife and nurse told my husband to go back home to pack his hospital bag (when we left the house we only grabbed my bag) but not to rush because we wouldn’t be having the baby for at least 12-16 hours.

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Stem Cell Therapy Information

Consuelo Mancias Guerra

Dr. Consuelo Mancias Guerra

The discovery of stem cells (SCs) has led to an ongoing revolution of medicine. Starting back in the 1950s, blood-forming SCs were first used to repopulate a patient's immune system. This was the first example of a successful SC therapy, and is still commonly used today for blood and bone-marrow-related cancers such as leukemia and myeloma.

Recently, the biology of SCs has created novel therapies for previously intractable conditions. One area where cell therapy has generated hope is neurology. Cellular therapy of the injured brain has been studied in preclinical models for more than a decade, providing the basis for the development of new therapies for a broad spectrum of human neurological diseases. The mechanism by which transplantation of SCs leads to an enhanced functional recovery and structural reorganisation is still not understood. Nevertheless, the use of autologous bone marrow-derived SCs does not face ethical, political, biological and regulatory hurdles, like embryonic stem cells does.

Cell therapy protocols for cerebral palsy are an example of a new approach to a condition that is difficult to treat. The current US clinical trials, listed in, are dependent upon the fact that parents chose to preserve their child's umbilical cord blood at the time of birth. Our clinical trial, listed as NCT01019733, was carried out at a University Hospital in Monterrey, Mexico, where we treated children with cerebral palsy that were not able to bank their cord blood. Instead we use SC derived from the bone marrow.

The patients enrolled in our trial received a subcutaneous medication for 4 consecutive days to stimulate their bone marrow to produce SCs, their bone marrow was then harvested, SCs were concentrated at the laboratory, and then they were delivered through the patient's cerebrospinal fluid on the fifth day of the procedure. In this trial, we made the translation from the laboratory to the clinic both medically and economically feasible. Our team conducted a thorough evaluation of each patient, from initial interviews to the final assessments. Patients came to us from different countries, including Mexico, US, Canada, Honduras, Colombia, and Italy.

The condition and response of patients in our trial was assessed at regular intervals to ensure the safety of the therapy. Even with this small group, less than 20 patients seen over 36 months, we were able to reach our goal, which was to demonstrate the safety of the procedure. This success opens the door to a phase II clinical trial that can test the efficacy of autologous bone marrow SCs. The preliminary results regarding efficacy were promising. We cannot say more, because the data are currently under review for publication. We hope that our work will offer a better quality of life to children with cerebral palsy.

In conclusion, while the field of SC medicine is rapidly maturing, many potential SC therapies remain theoretical or restricted to successes in animal trials. Countless studies are still required on the expanding frontier of SC research before a complete mastery of SC manipulation for maximum therapeutic potential can be achieved. In the meantime, we believe that patients with cerebral palsy can be treated with their own bone marrow SCs when their cord blood SCs were not preserved.

Dra. María del Consuelo Mancías-Guerra attended medical school in "Universidad Autónoma de Nuevo León" and graduated in general practice in 1992. She was trained in Pediatrics from 1993 to 1996 and then in Clinical Hematology from 1996 to 1998 in the University Hospital "Dr. José E. González" of the same University at Monterrey. She became a fellow in bone marrow transplantation and stem cells cryopreservation at the University of Texas in San Antonio from 1998 to 1999. She is board certified by Mexico's "Consejo Mexicano de Hematología". Since 1999, she is head of a private blood bank at the "OCA Hospital" in Monterrey, and since 2001, became part of the Hematology Service of the University Hospital in Monterrey. There she started the cryopreservation laboratory and the first public cord blood bank in Mexico. Dr. Mancías-Guerra participates actively in training medical residents and PhD students, has written more than 20 publications in medical journals, and 8 chapters in books about pediatrics and hematology. She has won several national awards of medicine. Her main area of research interest is cellular therapy, in which she has clinical trials running and listed in References Knoepfler PS. Deconstructing Stem Cell Tumorigenicity: A Roadmap to Safe Regenerative Medicine. Stem Cells. 2009; 27(5):1050-6. doi:10.1002/stem.37 Sng J., Lufkin T. Emerging stem cell therapies: treatment, safety, and biology. Stem Cells International. 2012; Article 521343. doi:10.1155/2012/521343 Carroll JE, Mays RW. Update on stem cell therapy for cerebral palsy. Expert Opin Biol Ther. 2011; 11(4):463-71. doi:10.1517/14712598.2011.557060 To learn more about cord blood banking, visit Parent's Guide to Cord Blood Foundation at

Dr. Frank Berenson's visit to Monterrey Mexico

First paralyzed human treated with stem cells has now regained his upper body movement


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